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The Deadliest Virus on Earth

  • Publicado em 25 Jul 2022
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    In the 1970s thousands of Chickenheads rained from the sky in Europe, making foxes and other wildlife confused and very happy. Why? They were filled with a vaccine to fight the deadliest virus known to humanity - since the 1930s a rabies epidemic had been sweeping across wildlife populations in Europe and humans wanted to finally get rid of the virus once and for all.
    Rabies is named after Lyssa, the ancient Greek spirit of mad rage, and has been haunting us for at least 4000 years. It can turn animals into angry beasts and humans into zombies that fear water. But what makes Lyssa fascinating is not just how bizarre and deadly its infection is, but also how incredibly good it is at avoiding our defenses.
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Comentários • 16 294

  • Kurzgesagt – In a Nutshell
    Kurzgesagt – In a Nutshell  2 meses atrás +3601

    Go ‘beyond the nutshell’ at brilliant.org/nutshell by diving deeper into these topics and more with 20% off an annual subscription!
    This video was sponsored by Brilliant. Thanks a lot for the support!

    • Daniel Martin
      Daniel Martin Mês atrás

      I have a question for the experts:
      In context of Sri Lanka, which recently in August of 2022 saw 25 deer die from Rabies, could this signify an actual Zombie Outbreak?
      The idea formula is this:
      If COVID-19 can infect a human and cause Long COVID Brain Fog, then why couldn't it also do so in dogs? If dogs fail cognitively to relate to humans, wouldn't they be more prone to social aggression, rendering domestic bliss for a feral disposition?
      Deer have become a reservoir species for COVID-19 but don't typically experience its symptoms, but are able to infect humans and pets in hand feeding situations. The 25 deer that died in Sri Lanka were in a community that does hand feed them regularly.
      Assuming the deer infected the humans with COVID-19, who then infected the dogs with COVID-19, who then went feral with Brain Fog, then became infected with Rabies, which then attacked the deer, and the deer died from Rabies, but did any of the rabid deer infect the humans?
      This is important to ask, because COVID-19 has a neat trick of turning body fat as replication fuel into a meat shield within a clumping of infected cells, any of which could harbor a Rabies virus cell like a Trojan Horse, thereby "Airborne Rabies" via coughing droplets.
      If Rabies learns to partner with COVID-19, this in my opinion could constitute a Zombie Outbreak, presently in the feral dogs and possibly the wild deer for now.
      Sri Lanka is presently in a socially collapsed state, their island nation doesn't function properly at this time. Those who are freshly infected with COVID-19 might flee to other countries for a more stable life, with the risk of a Rabies that came undetected with it. A rabid person by madness isn't going to wear a mask or be socially distant, even more so any infected dogs or wildlife that leaves Sri Lanka. If a COVID-19 infection coughs with Rabies particles, no bite is required, just inhalation. We also need to remember that vaccines only prevent the severity of symptoms of COVID-19, it would create a false sense of security against any development of Rabies.
      Now imagine this happening in America, as people dump their pets into city streets out of panic when any sign of illness in the family or pets happens, that no conventional lockdown could work as people still need to exit their houses to get basic supplies, and many Rabies attacks are very common at driveways and parking lots.
      Maybe that's where science fiction got it wrong, it wasn't the humans who were the zombies, it was to be our pets?

    • HP Cuthulu
      HP Cuthulu Mês atrás


    • Michael Arch
      Michael Arch Mês atrás

      5:08 is perfect

      DEATHTM Mês atrás

      @Vellfire GG other viruses are deadlier bruh.

  • Joe G
    Joe G 2 meses atrás +9934

    Lyssa is basically running the optimal Pandemic/Plague Inc. strategy. Super stealthy until the target is fully infected, then rapidly turn extremely lethal

    • German Fisch
      German Fisch Mês atrás

      @Mal-2 KSC start in greenland

    • Evan Johns
      Evan Johns Mês atrás

      @Xanboyyy That’s probably why there is one countermeasure for poor transmissibility. Animals that act as carriers without suffering from rabies, like armadillos, keep it alive until they infect creatures that can suffer from the virus, causing the virus to thrive in spite of its one weakness 🦠

    • TheCoolGuy :)
      TheCoolGuy :) Mês atrás

      @Phraker is it unrealistic if we are talking about potentially weaponized diseases?

    • The Under Nerd
      The Under Nerd Mês atrás

      @the dank soul I think you missed the strategic point here 😭

    • Raul Menendez
      Raul Menendez Mês atrás

      That is not the best way. Just get necrosis and bam

  • bir liso
    bir liso Mês atrás +410

    Kurzgesagt : “Your immune to every virus possible” Also Kurzgesagt : ”not this one lol”

    • literal antifa terrorist
      literal antifa terrorist 5 dias atrás

      @Stove Face That's what happened? I just thought the Panther crew was taken by surprise.

    • dirhi
      dirhi 9 dias atrás +1

      stop liking this comment its a bot bruh

    • Stove Face
      Stove Face 15 dias atrás +3

      @UC8xVAvYYlp3hj1g3a67NJFw you need to have a specific mutation on your CCR5 gene, HIV needs both CD4 and CCR5 in order to latch on and enter the cell but if both of your parents have the mutated gene then the CCR5 receptor isn't outside of the cell and since most HIV strains need it to enter it makes your immune or at the least resistant it

    • Stove Face
      Stove Face 17 dias atrás +10

      I mean technically it can, the body realizes something is going and acts upon it, only issue is that it uses friendly fire on it. It's like the tank duel in Cologne, the panther crew went around the corner and didn't recognize the Pershing as a threat and thought it was a friendly until it shot them

    • maria fe
      maria fe 25 dias atrás +4


  • Amy Tinkle Me 4 [S]E.X
    Amy Tinkle Me 4 [S]E.X Mês atrás +843

    When I was 19, an erratic bat that crashed with almost every object around entered in my house, and when I tried to grab the creature to throw it back outside, it bit me. My mother was highly concerned about what just happened, she seemed almost hysteric and I of course thought she was overreacting. She took me to a clinic that same night and made me take the anti-rabies vaccine, the first shot of many that I had to take in order complete the treatment.
    Reading afterwards about the awful and agonizing death that rabies patients suffer when they are left unattended, I am very grateful to my mother for her urgency and don't wanna think too much about what would have happened if she hadn't been around to act so quickly and decidedly. Most probably I would have forgotten about the bite the next day and would have died in the next few months. She saved my life.

    • dirhi
      dirhi 9 dias atrás


    • Lynn Huang
      Lynn Huang Mês atrás

      @skritch S It's probably a bot that just copies other comments

    • Table leg Z
      Table leg Z Mês atrás

      @Emma Philo well in any case better to be safe than sorry

    • Jeweled Skeleton
      Jeweled Skeleton Mês atrás

      @skritch S Chatbots are evolving.

    • Eon Thinker • 100 yr ago
      Eon Thinker • 100 yr ago Mês atrás

      @skritch S yeah your right your comment is crying skritch S

  • Storm Evans
    Storm Evans Mês atrás +183

    This is one of the craziest cellular biology animations ever, you really packed this one full of the amazing stuff, I didn't know any of these intricacies of the immune system and I feel like everyone should have a working model like this in their head of what's actually going on inside them.

    • Ask to seduce Miss
      Ask to seduce Miss Mês atrás +1

      treatment after being bit by a rabid animal will result in one of the most horrible deaths known to mankind, therefore praise the science!

  • scientia est potestas
    scientia est potestas Mês atrás +159

    I always thought HIV was the sneakiest and scariest of viruses bc its "life" cycle is the equivalent of a swarm of deadly ninjas sneaking up on the most crucial parts of your immune system "army", going undetected right under their nose, and then taking them out with a single deadly punch to the throat. But then I saw this and realized that Rabies does all that but with the twist of torturing you to death 😳

    • Mid Ocean
      Mid Ocean Dia atrás

      as someone who's currently studying HIV for a biology exam tmr, thanks for the illuminating description, i really need it

    • Evil Sharkey
      Evil Sharkey 29 dias atrás +4

      And rabies has a 100% mortality rate except for a handful of people who’ve been treated with extremely intensive medical interventions and had to recover from serious brain damage. With the newer drugs, HIV is still incurable (it will come back if you stop taking the drugs), but it’s no longer a death sentence.

  • Tux
    Tux 2 meses atrás +47535

    It has been suggested that the vampire myth originated from people infected with rabies. Since rabies causes light hypersensitivity, hydrophobia, aggression, and occasional biting, it fits the narrative of a typical vampire who goes out at night, is scared of holy water, and sometimes bites people. It’s interesting to think about anyway!

    • UnluckyOmens
      UnluckyOmens 19 dias atrás

      Wasnt there also a very rare skin condition that was only in like 2 families where the skin was so thin that it was light sensitive and the gums bled that was linked to vampires? Saying it out loud i think my brain mightve made that up but i swear i watched a video on it

    • 리드
      리드 25 dias atrás

      @Pale_Oblivion ㅋㅋㅋㅋㅋ

    • corgi master
      corgi master Mês atrás

      And in some cases
      They can't cross water

    • Alexander Crash
      Alexander Crash Mês atrás

      Was rabies originated in Transylvania? Not being smart but that'd be funny.

  • carlinianam0s
    carlinianam0s Mês atrás +58

    I have been absolutely terrified of rabies for many years. It scares the absolute living crap out of me, even though it isn't something I really have any real need to fear - I don't spend an inordinate amount of time outside or near wild animals. It's not something I'll likely encounter, but as soon as rabies comes up in a conversation, I break out in a cold sweat.
    This was my first Kurzgesagt video that I've ever watched. Of _course_ it had to be about rabies.

  • Fade 🇺🇦
    Fade 🇺🇦 Mês atrás +70

    I love how he makes the entire explanation feel like a spy movie where they have to infiltrate and take down a huge compound and use it for themselves

    • Ask to seduce Miss
      Ask to seduce Miss Mês atrás +2

      This channel never disappoints and the quality is always to such a high standard, thank you for teaching me so much Kurzgesagt!

  • Chef Jon Kung
    Chef Jon Kung Mês atrás +143

    I am such an immense fan on this channel. I would have done so much better in school if this were around then! I hope you’re so immensely proud of what you do because the value you add to BRclip and the world is huge.
    Thank you.

    • jupiter3067
      jupiter3067 Mês atrás

      Those guys were themselves to school one day and learned what they are teaching now.
      The school format is perhaps not made for everybody. I agree.
      But I think your spirit is now more open to learn that's perhaps why you think you would be more interested to learn.
      I personally adore my school years. 95% of my teachers were interesting (or was I interested to learn ?)
      I remember every single morning of school I expected to learn something new and to use this knowledge to understand the "Big picture" surrounding me.

    • Joanna
      Joanna Mês atrás

      would take my kid to get it checked. So happy there's more information nowadays like these videos :)

  • Vojta Dolezal
    Vojta Dolezal Mês atrás +26

    Really really nice video. As a molecular biologist who plans to study and specialise in Virology, I really apreatiate the simplicity and yet absolutely exact informations. Also, the detail of very beautiful animation is admirable

  • Simeon Georgiev
    Simeon Georgiev 2 meses atrás +4618

    Im a biologist and I’m always fascinated how you manage to explain complex mechanisms in an easily understandable manner. Great job once again!

    • Petrol_Forever
      Petrol_Forever 16 dias atrás

      @Hufman Don't be jelly dude

    • Limi V
      Limi V Mês atrás +1

      @Mo Gh It has been a while since I've watched the video, but I think it was in reference to cells that are not immune cells. The immune cells are like a military, so the other cells are civilians

    • Mo Gh
      Mo Gh Mês atrás

      What do they mean with "civilian cells" ?? 2:49

    • Limi V
      Limi V Mês atrás +1

      I think the animators do a lot of the heavy lifting here, though of course the explanation are definitely good

  • Utsav Shrestha
    Utsav Shrestha Mês atrás +18

    Imagine if we were taught science this way from a young age. Maybe we would take it for granted if that was the case, but man it would be great.

    • Olaoluwa Faleye
      Olaoluwa Faleye Mês atrás +1

      Exactly he made it so simple and interesting

  • DamitCarl
    DamitCarl 4 dias atrás

    It would be really interesting to go over the case where they put a victim into a coma and they survived the last stage of rabies

  • minij hooi
    minij hooi Mês atrás +2

    It's actually pretty scary how good nature can be at killing us. Gives us a good perspective of how fragile we are.

  • misterwu
    misterwu Mês atrás +8

    Love your videos! Please do one about prions (and proteins in general)! It's a very interesting and complex topic

  • CG M
    CG M 2 meses atrás +11624

    It's actually pretty scary how good nature can be at killing us. Gives us a good perspective of how fragile we are.

    • Bunsenn
      Bunsenn 11 dias atrás

      @Alex Belardo A human can survive an entire car hitting them if it’s at the right angle, but if they fall wrong they become paralyzed from the neck down. It’s so fucking weird.

    • human of the idiot variety
      human of the idiot variety Mês atrás

      the human body is complex and good at doing what it does, but as with many things its also stupidly flawed in many ways

    • Gandalf the Grey
      Gandalf the Grey Mês atrás

      @FutureGMChess We are by far not the only species that collaborates in large numbers to solve a problem.

    • Gandalf the Grey
      Gandalf the Grey Mês atrás

      @George Jones Yeah. Just think of Horses and one of their most likely injuries (both domesticated and in nature): A broken leg.

    • Gandalf the Grey
      Gandalf the Grey Mês atrás

      Or it shows what absolute monsters our immune system is and what humans are capable of.
      I wouldn't call a lion fragile just because he succums to me throwing spears at it.
      The spear are designed to kill it, after all.

  • Matthew Ashley
    Matthew Ashley Mês atrás +21

    This channel never disappoints and the quality is always to such a high standard, thank you for teaching me so much Kurzgesagt!

  • evanfmc
    evanfmc Mês atrás +12

    This is one of the most terrifying biology lessons I've ever gotten.

  • Roberval Moraes
    Roberval Moraes Mês atrás +5

    Hey! I am a university professor in Brazil. I teach Immunology classes and I would love to dub some of your videos in Portuguese to help my students learn. Not for profit anyway. Just for easy access! Your work is amazing and I would like to share it that way. Of course all credits would go to you. I can put the link to your videos and the book. It would be possible?

  • Shevchenko 7cfc
    Shevchenko 7cfc Mês atrás +5

    This was incredibly informative, I thought I had an idea of how wildly bad rabies was, had no idea just how bad tho. great video!

  • blackcorvo
    blackcorvo 2 meses atrás +5667

    Fun fact: opossums usually don't get rabies, because their body temperature is too low for the virus to survive in them.
    They're literally too cool for rabies!

    • Bunsenn
      Bunsenn 11 dias atrás

      What if you lowered the body’s internal temperature in a controlled, medical environment in order to kill the virus off? Could that work in some way?

    • Miles Edgeworth
      Miles Edgeworth Mês atrás

      @Justin C. 🤓

    • Queeniieee
      Queeniieee Mês atrás

      @Dona Countered, fatherless issue.

    • Dona
      Dona Mês atrás

      @Queeniieee skill issue

    • Zenitsu Agatsuma
      Zenitsu Agatsuma Mês atrás

      @1lz Skill issue + ur a mistake + I have a dad + touch grass

  • Ragnar
    Ragnar Mês atrás +42

    can we just appreciate the fact that something with THIS amount of quality is free

  • Gandalf the Grey
    Gandalf the Grey Mês atrás +1

    Rabbies is something really scary to me personally.
    When I first heard about it when I was a small child I though it's some flu type of thing that sometime later just stops.
    It also has a "funny" name in my native language German: "Tollwut" which, to me as a child meant "Great anger" or "Anger I enjoy" (besides, the "toll" is actually an old German word for something entirely different).
    Yeah, when I learned what Rabbies actually is and it's survivability.... my world shattered.

  • superbray 1
    superbray 1 7 horas atrás

    Another great video Kurzgesagt. I especially love these videos of microbes and diseases. It led me to buy your book all about microbiology. I hope you do more videos about diseases and medicine

  • Storm Evans
    Storm Evans Mês atrás

    Makes me think of those movies about bioweapons that turn people into "zombies" that are based in reality. Could you imagine weaponized rabies that only targets populations of European descent or something like that?

  • TheJP100
    TheJP100 2 meses atrás +4673

    As someone who has been saved by the post-exposure vaccine for rabies, I can barely explain how thankful I am for this invention! It is really unpleasant, yes, but not getting that treatment after being bit by a rabid animal will result in one of the most horrible deaths known to mankind, therefore praise the science!

    • Connor Norris
      Connor Norris Mês atrás

      @Limi V trust me its not bad at all.

    • Limi V
      Limi V Mês atrás

      @Connor Norris As a needle-phobic, I don't find that very reassuring

    • Connor Norris
      Connor Norris Mês atrás

      its not unpleasant really, just a few shots.

    • Limi V
      Limi V Mês atrás

      @kilderok I think it's more likely the cost of developing a new or improved treatment when the existing one works perfectly fine is the issue. Almost any change to a medication or its production methods necessitates new approval from regulatory agencies, and that takes a lot of time and money

    • kilderok
      kilderok Mês atrás

      I kind of feel like it is this "better the horrible shot than a horrible death!" mentality that is the reason why they haven't made the shot less horrible.

  • Aste
    Aste Mês atrás +4

    2:15 I think you mean it looks like an AT-RT from Star Wars! 🤣 In seriousness though, the whole clip from 2:15-4:15 is absolutely mind-blowing. I almost can't believe this is part of how the body works at the cellular level! Thanks for another amazing video!

  • Blob_King6112
    Blob_King6112 Mês atrás +2

    I've heard theories that you die because you are afraid of water and eventually lose a fatal amount of water within your body, but I'm not sure. I'm from the UK and we've eliminated rabies here, but its still scary that rabies is so deadly. I'd be interested to hear what other people think kills an infected person. Also this is kinda the basis for the movie 'INFECTION', which is rabies + drugs = instantaneous zombie virus.

    • Raphaël D
      Raphaël D Mês atrás +1

      In the articles I've read, it is stated some patients die after the virus sabotages the links that allow us to breath unconsiously. This means that after this stage, every single breath they take has to be a decision of their own, like you would devide to raise your arm or walk. And with the patients being already in a constant panic state, it probably is too much for them to handle.

  • Dadunddd.a D
    Dadunddd.a D Mês atrás +1

    It's interesting to realize that the only reason we have survived and avoided a zombie-apocalypses is that we can control ourselves from biting one another with teeth.

    • Subaru
      Subaru 27 dias atrás

      Or we are just more likely to punch then bite

  • KnallisSillan
    KnallisSillan Mês atrás +6

    My favorite thing about this video is the using of the word, "glimpse." This channel is very good at saying a lot with very few words, and not only was this only a glimpse, but that was such perfect word choice that it really sums up what makes Kurzgesagt so enjoyable. A glimpse is all you need to want to learn more.

  • B M
    B M 2 meses atrás +2174

    Props to the storyboard artist or concepter or whomever in production who decided the person in the animation to be infected should be a child rather than one of the birbs, adds a real oomph emphasizing the scary reality of rabies

    • 877-Cash-Now
      877-Cash-Now 2 meses atrás +2

      Rabbies only affects mammals, so it wouldn't be entirely accurate if they did

    • Nadarith
      Nadarith 2 meses atrás

      @Zephroze Rabies can't infect birds

  • swisse peach
    swisse peach Mês atrás +3

    Learning about the immune system is crazy, all these little things are working so hard just to keep you alive, and yet you barely even think about it

  • Dylan Finch
    Dylan Finch Mês atrás +1

    To be totally fair though, humans rely very little on biting when we feel threatened. Animals like dogs, cats, squirrels, etc. Usually resort to biting first. Humans tend to kick or punch, or most likely grab weapons when we feel threatened, so that's probably why humans biting each other isn't very common, even with rabies.

  • tylerhaunted
    tylerhaunted 21 dia atrás

    I love how we have these little biobots in our bodies that's composed of proteins and have been operating in our bodies since birth. Amazing stuff

  • el gerrano
    el gerrano 24 dias atrás +1

    Yk it’s really unnerving how long people can go without knowing they have it. For example a man who went to Brazil (correct me if I’m wrong on the next part) and got bitten by a cat carrying a strain of the virus that had an incubation period of almost 10 years. But thankfully it’s easier to get the bubonic plague than rabies.

  • KingRedWolf 88
    KingRedWolf 88 Mês atrás +3

    So I only started watching your videos just recently and I really enjoy the entertaining visuals along with a easy to understand lesson. But man I couldn’t remember the name of the channel at all. Y’all got me looking up “Science videos with those birds.” Into google. Great stuff keep it up.

  • AnyasCelticCreations AtEtsy

    This was awesome! Could you do one on Lyme disease please?

  • BOB Joatmon
    BOB Joatmon Mês atrás +1

    As a kid growing up rural we were indoctrinated early on common dangers and how to avoid them. But I noticed that city folk were not taught much of anything and so had lots of incidents (and I'm sure country folks going to the city seems pretty dumb about city dangers too).
    I don't actually remember when I was told to watch animal behavior, it's just something you do as a kid but I remember some city cousins I warned about watching for snakes as they played on the woodpile at around 4 1/2 or 5.

  • Bryan Sprecher
    Bryan Sprecher Mês atrás

    Truly amazing. We should structure society more like microbiology.

  • Wither
    Wither 2 meses atrás +4043

    i swear to god the microscopic world of the immune system is the most involved and elaborate RTS game in existence its actually insane.

    • Stephen 777
      Stephen 777 11 dias atrás

      Just plain old vitamin deficiency. Vitamin A creates sensitivity to light. lol.

    • Sefyra Velvetpaw
      Sefyra Velvetpaw 20 dias atrás

      I would pay for a game like that

    • shannon edgar
      shannon edgar 29 dias atrás

      holy fuck your right

    • Out of the box
      Out of the box Mês atrás

      And some say it was a accident.

  • Arjun
    Arjun Mês atrás +1

    I am a kid and when you said"Almost half of them are children"I was very scared btw I love the educational videos

  • Péter Szilvási
    Péter Szilvási 15 dias atrás

    If you are read the *Immune: A Journey into the Mysterious System That Keeps You Alive* then you would probably preciate this video more. Thank you for the amazing animation as always! 🙂

  • Trishit Das
    Trishit Das Mês atrás +6

    Thank you kurzgesghat team to give information about this lyssa virus. 47 years ago my grandmother had passed away in a village, but no one knew that how had she died! Today I understand how she died at that time due to virus😔... Thank you for this video ❤️

  • Danual Scarbrough
    Danual Scarbrough Mês atrás

    Would love to see a video on what type of resources we would need to become a type 2 civilization

  • Katherine
    Katherine 2 meses atrás +276

    This is definitely one of the most frightening yet interesting things I've ever learned about!
    Too bad Kurzgesagt upload so late in the evening in my timezone, I will probably dream about scary viruses tonight 😮

    • Lucifer
      Lucifer 2 meses atrás +1

      @VIX Yes, I live in biggest city of India Mumbai at 74th floor of my complex and I'm poor and awfully managed 😄

    • hiklu
      hiklu 2 meses atrás

      @Lucifer you are literally anime lucifer, how can you be scared by anything?

    • HB
      HB 2 meses atrás


    • VIX
      VIX 2 meses atrás +1

      @Lucifer and because Lucifer published at 2AM 3hours ago, I know, based on my position, that Lucifer must live somewhere pretty awfully managed as India or or Kazakistan or wherever y’all treat women as runner ups

    • VIX
      VIX 2 meses atrás +1

      In my timezone uploads mid afternoon and I’m always working, I’m watching it at 2AM anyway tho

  • Lindsey Palmer
    Lindsey Palmer Mês atrás +1

    Thank you for this video I didn't know rabies was the deadliest virus on earth. I want to check and make sure I got my rabies shot when I was younger

  • Toon
    Toon Mês atrás

    I learn about this in school, it’s really impressive how you nail every single aspect.

  • Hugo Bounoua
    Hugo Bounoua Mês atrás +1

    Amazing quality content, drawings and animations!! Very impressive and informative. Count me as a new subscriber!

  • GuffinMcGuffin
    GuffinMcGuffin Mês atrás

    It would be extremely great if there would be found a way to cure rabies after th sympthoms are manifested - like in the Milwaukee protocol.

  • Yutah Kotomi
    Yutah Kotomi 2 meses atrás +3730

    I knew of its fatality rate, but never knew rabies was this insidious with its process.
    Glad it isn't _very_ widespread.

    • The other John Smith
      The other John Smith Mês atrás

      @Ninja Kitteh because you seem to be able to downplay complex processes in the world with wording like "the world doesn't give a fuck", while in fact many fucks have been given, and will continue to be given.

    • Ninja Kitteh
      Ninja Kitteh Mês atrás

      @The other John Smith What makes you think I think the world is simple?
      Mate, there's a reason the saying goes "it's only a war crime if you lose the war"...
      Oh, to be that innocent again...

    • The other John Smith
      The other John Smith Mês atrás

      @Ninja Kitteh Yep really. The evil powers at play will break treaties. But a war fought by a good power (there *is* such a thing), will not resort to such practices. This is why treaties exist. To keep the good, good. And to punish the bad, when they do bad.
      Just saying, the real world is not as simple as you think it is. And it, demonstrably and repeatedly, does actually give a fuck.

    • Ninja Kitteh
      Ninja Kitteh 2 meses atrás

      @The other John Smith No, really? I'm ever so shocked.
      Just saying, the real world doesn't give a fuck.

    • The other John Smith
      The other John Smith 2 meses atrás

      @Ninja Kitteh Just saying, breaking treaty is a war crime.
      Just like sppeding will get you a speeding ticket.

  • DeadDuckMagic
    DeadDuckMagic 19 dias atrás

    Everything abt this channel is amazing. The voice the subject making learning so enjoyable. Thank you

  • Rex Valle
    Rex Valle Mês atrás

    I feel like my body is a universe in itself with all these battles and death going on inside me. Makes me question if our universe is also just a body of an even larger being and that we are but equivalent to cells in that body.

  • Dan Powell
    Dan Powell Mês atrás +2

    Just here to appreciate the subtle Wilhelm scream at 7:58, since no one else seems to have mentioned it. Enjoyed the video very much, also loved learning about the transparency trick!

  • Ari Dreams
    Ari Dreams Mês atrás +9

    This is a super interesting disease, and I find it intriguing that we don't really know how people die from this disease. Like, yes, there is the paralysis, numbness, and coma, but I find it interesting that it can also cause seizures in some cases. I suspect that they hijack the neurons to where they cannot properly communicate with one another effectively allowing the host to be paralyzed to death. AKA there is little communication with the organs, and maybe the brain isn't able to commit to the actions needed for survival. OFC the sis simply an idea. If I had to choose, I would love to use my degrees in the direction of rabies (after symptoms show) or any sort of filoviruses which are also not a pleasent thing to deal with.

  • Narokkurai
    Narokkurai 2 meses atrás +3036

    I remember reading that one of the most-affected parts of the brain by rabies is actually the amygdala, which controls a person's fear response. It essentially gets permanently switched on, so not only are you in agony as your brain expands and your muscles spasm uncontrollably, but you are trapped in a permanent state of terror where everything and everyone seems like a threat to you.

    • Keep dat same energy
      Keep dat same energy 18 dias atrás

      @Nad Do no, your just crazy

    • TheAdvertisement
      TheAdvertisement 26 dias atrás +1

      That's probably part of the reason hydrophobia happens so easily too- they aren't just unable to swallow right, they're quickly afraid of it-

    • Subaru
      Subaru 28 dias atrás +3

      I guess that makes sense. The virus would need animals to bite in order to spread the disease, triggering fear sounds like a good way to do that

      JOE MAMA GAMING Mês atrás

      I do not want to die like that

    • Walter 🇺🇦
      Walter 🇺🇦 Mês atrás

      @type7 im Filipino!:D

  • Dr. S W
    Dr. S W Mês atrás

    I was a house officer physician long time ago and early morning an old man brought his teenager son to us. I went close to the boy and asked him how he was. All of sudden he shrieked, scarring me as well. The dad told me he was bitten by a rabid dog a few weeks ago. I understood, the poor boy had rabies. And it's mortality is nearly 100%. Sad case.

  • Ray Kyle De Castro
    Ray Kyle De Castro 19 dias atrás

    I'm gonna officially name my dog lyssa, I wonder if I get weird stares at the vet. 😂

  • Na Lusan
    Na Lusan Mês atrás

    the way this virus works reminds me on MS. where in fact i am treated with a weekly dose of an interferon . and the symptoms of lyssa in the brain are well known to any other MS patient too.

  • Jeremiah Wollander
    Jeremiah Wollander Mês atrás +1

    Love your content. You should do a video about helium. Uses, shortages, means of production, etc.

  • MADank
    MADank 2 meses atrás +1522

    The most interesting and also haunting part about rabies to me is the strong hydrophobia people display. Its such a specific and scary symptom that by chance also helps you spread the virus better because you wont dilute your saliva with anything else.

    • True Vision
      True Vision 2 meses atrás

      Someone sent me this very serious interesting video (regarding Mental Health & The Creator). Alternatively, you can acquire it in Doc/PDF format, or read it online in the description box via directory link.

      Find it on * True Vision * and their BRclip channel, or insert the following title in to your BRclip Search Box: * G only is responsible for everything *.

    • SænaNartaa
      SænaNartaa 2 meses atrás

      Perhaps even more hauntingly, not every rabies patient displays hydrophobia. Because we are all unique individuals, and the brain is such a complex organ, rabies symptoms are very diverse. This is just one reason why it's a very difficult disease to diagnose.

    • deez land
      deez land 2 meses atrás

      idk if your right cuz i vary dum i only in 3th grade

    • Sönke Schmidt
      Sönke Schmidt 2 meses atrás

      @mahmoody until it gets back into the ocean. Then it's no longer a strength.

  • Trumps-gay-lover
    Trumps-gay-lover Mês atrás +1

    When I was in India I stayed near a rabies hospital for two nights, and it was absolute disturbing. It was more like a prison, you could hear screaming and people begging to be let out saying they didn’t feel sick anymore. Scary shit.

  • Tetteh Kwadjo
    Tetteh Kwadjo Mês atrás +1

    Its amazing how billions of years of random evolutionary chaos can lead to such complex systems.

  • Shrekstermeister
    Shrekstermeister Mês atrás +1

    I am so glad I read the immune book it made me feel like an expert 🤓

  • freeland 2
    freeland 2 Mês atrás

    Thank you kurzgesagt. Your knowledge has made me a smarter person. Keep up the good work!

  • TC
    TC 2 meses atrás +2538

    I find it interesting that humans went from using sticks and stones to somehow finding a way to figure out how each cell in the body works

    • Marlon Valcq
      Marlon Valcq Mês atrás

      Evolution and innovation

    • Arsh Akber
      Arsh Akber Mês atrás +1

      @Agustín Franco probably 200,000 if he is telling the truth

    • Nadarith
      Nadarith 2 meses atrás +1

      @True Vision That's even worse, truly contemptible

    • True Vision
      True Vision 2 meses atrás

      @Nadaritherrggheeergggghhgfgh. No bot here just spam time!

  • Holly Bee
    Holly Bee Mês atrás

    I got bit a few weeks ago in Zambia. I had two pre-exposure shots and am completing my post-exposure course next week. Man, this video is scary and spookily timed.

  • Out of the box
    Out of the box Mês atrás +1

    2:18 How can some people think that this is a coincidence, this is pure engineering.

  • Paule Anonuevo
    Paule Anonuevo Mês atrás +1

    I wanna personally thank the whole team from research to animations for creating this. I hope we continue to see more of Immune System series, it's both scary and beautiful!

  • 204bookish
    204bookish Mês atrás

    Wow this is my first video I watched of this channel, and I'm blown away by the rich info and adorable animation style! You've earned another subscriber! XD

  • elisgus
    elisgus 2 meses atrás +1853

    These guys should have an entire tv show, these videos are so high quality it’s unreal.

    • True Vision
      True Vision 2 meses atrás

      Someone sent me this very serious interesting video (regarding Mental Health & The Creator). Alternatively, you can acquire it in Doc/PDF format, or read it online in the description box via directory link.

      Find it on * True Vision * and their BRclip channel, or insert the following title in to your BRclip Search Box: * G only is responsible for everything *.

    • Nethiuz
      Nethiuz 2 meses atrás

      No thanks, TV has ads and is old world, heck you have to be present at a set time.

    • Shade
      Shade 2 meses atrás

      Well, it's better than that since YT's audience is much wider than a single TV channel's reach. Especially in times when mass censorship arises anew.

  • F.Gökhan Atlas
    F.Gökhan Atlas Mês atrás +1

    Aşı karşıtlarının izlemesi gerekiyor. Neredeyse tüm aşılara karşılar ve çözümünü bulduğumuz hastalıklar bile tekrar görülmeye başlandı…

  • Alexander Gertz
    Alexander Gertz 25 dias atrás

    Actually, there is a treatment for rabies once the symptoms start. It happened back a few years ago to a girl in highschool that was bitten by a rabid bat.
    To briefly explain, when rabies infects the host, it is slow. Really, reeeaally slow. It has mastered the art of moving so slowly, it turns invisible. As the video explains, rabies is one of the hardest viruses for the immune system to detect. Once it reaches the brain stem it's pretty much over.
    Even though the body is failing and dying, the immune system doesn't go down without a fight. You see, in the bodies of people who passed due to rabies, they found traces of antibodies specifically targeted towards rabies. It's not invincible. Once the virus plays its hand and reveals itself, the dendritic cells can react and get the killer t-cells on scene.
    The major problem is that, well, you're probably dead at that point.
    So some really smart, and extremely desperate doctors realized that all they have to do is to keep the body alive long enough in order to let the immune system fight.
    So, what they did is that they put her in an induced coma for about little over 2 weeks. The doctors would periodically monitor her to ensure that she was producing antibodies and check for the virus. They would also 'wake' her body to see if she could be safely revived.
    In the end, she survived.
    To emphasize this was an extremely dangerous and risky operation. Any sort of coma even induced one can cause long-term harmful effects. The doctors honestly thought that she might end up brain dead. Trapped within her own body unable to move, see, hear, or smell anything. This was a last ditch desperate move. And yet it is one of the only recorded cases of someone with an advanced case of rabies successfully surviving.
    Just goes to show you, that even when your brain explodes, your lungs go on strike, or your liver tries to exit your rectum or something. Your immune system will stick by you to the bitter end.

    • Raphaël D
      Raphaël D 25 dias atrás

      This process has been called the Milwaukee protocol, so far it has worked for 6 patients. As you said, it is not wothout risk and far from a guaranted success, and in fact, it has been stated the first version of this treatment was tried on 25 patients who had all the conditions to survive the illness, with 23 of them dying anyways. Then other attempts raised this number to 6, but that's as far as it seems to get unfortunately

  • mrcelada
    mrcelada Mês atrás

    Some people survived serius rabies syntomps, resulting in neurologial aftermath, that ended up reversing at high degree with time.

  • Colin Burke
    Colin Burke Mês atrás +1

    This video ended up trigging my vasovagal syncope (i.e., fainting) around the time it got to the "virus at the brain stem" bit. I've previously had it happen when: I read about organ theft, watched the bit on the first Matrix where Morpheus talks about "watched them liquify the dead to feed the living", and when the bad guys tried to kill Duck by draining his blood on a Halloween episode of NCIS.
    Could you fine folks do a video on vasovagal syncope?

    • Connor Norris
      Connor Norris Mês atrás

      thats really interesting. you must be very sensitive. thats a good thing.

    • Colin Burke
      Colin Burke Mês atrás

      @yessir! No, it's more complicated/specific than that. Upon reflection, it seems to be a combination of gore/blood/organs, helplessness, and being violated. Individually they don't cause it, and even together it doesn't always seem to happen, but it seems like that combo of factors, in the right way and the right time, can make me pass out.

    • yessir!
      yessir! Mês atrás

      so you pass out when exposed to terrifying information?

  • MilkThrower
    MilkThrower 2 meses atrás +2806

    Honestly, I thought rabies was just "Woah-ho! that dog is foamin' from the mouth! Don't go near it, they're aggressive!" but this video has actually shown me what happens, and I'm so happy that these videos exist

    • Mike Jones
      Mike Jones Mês atrás +1

      @BYERE I have seen a video (I think on BRclip) of a guy in the hydrophobia stage of rabies. That was horrible to watch.

    • H2O Bear
      H2O Bear 2 meses atrás

      @CuteBabySeal how strange that they left it at hey this is awful get vaccinated instead of showing such disturbing information that you would write that 🧐

    • SænaNartaa
      SænaNartaa 2 meses atrás

      Rabies hosts can be asymptomatic during viral transmission too

    • Ignatius C
      Ignatius C 2 meses atrás +2

      @Fionna Clarissa Muharlie there are multiple known cases of cats spreading rabies to humans. Free roaming cats also further spread rabies to dogs and other animals

  • たいやきミー
    たいやきミー 28 dias atrás


  • Xboxroadhogmain
    Xboxroadhogmain Mês atrás

    Man we are SOOO complicated, really makes you wonder how we found all of this out.

  • Lam Lam
    Lam Lam Mês atrás

    That's what i exactly thought,how dangerous rabies is,,,seeing a video of someone effected by rabies and how they were avoiding water was scary

  • Ragnar
    Ragnar Mês atrás +1

    It's amazing that this channel is run by cute birds who hired a human narrator for educating humans.

  • Infinity Plus 1
    Infinity Plus 1 2 meses atrás +992

    It’s crazy that 5 genes in a shell is able to kill us almost 100% of the time. Really shows how fragile the human body is

    • Ghuirm
      Ghuirm 2 meses atrás

      more like 99.5% of the time as some people manage to miraculously survive a infection once symptoms are shown

    • Yilmaz Ayten
      Yilmaz Ayten 2 meses atrás +1

      And at the same time there are bacteria which would kill another mammal in days have no effect on us. Theres a sheath for every sword in nature.

    • CantEaters
      CantEaters 2 meses atrás

      @TickTock Bam its not 100, but very near to 100. There are 29 recorded cases of survival, all after 2000 IIRC

  • Evil Sharkey
    Evil Sharkey 29 dias atrás +1

    Since the discovery of the Milwaukee Protocol, there have actually been dozens of survivors of symptomatic rabies, way up from zero. Basically, the Milwaukee Protocol involves putting the patient into an induced coma for weeks or months to protect their brain while pouring in a cocktail of drugs to help the immune system slowly fight off the infection. There is residual neurological damage that requires a lot of therapy to recover from. Unfortunately, such a treatment is astronomically expensive and resource intensive, so unavailable for a lot of people.

    • Raphaël D
      Raphaël D 26 dias atrás

      I'm also pretty sure it didn't save dozens of patients. Success rates were so low that scientists adviced against it...

  • June Zhang
    June Zhang Mês atrás +12

    When I was 9, one day on my way to school, a drooling aggressive dog, came out of nowhere and bit me on the left hand, left a lot of drool on the wound.
    I went to school, showed it to the teacher, she got my mother, then I was taken to the hospital and got a vaccine, close call...
    There's still a visible scar on my ring finger today.

  • marksuave25
    marksuave25 Mês atrás

    So thankful that I live in today's world. There is at least a vaccine for this if you ever get bit.

  • Ali Youssef
    Ali Youssef Mês atrás +7

    kurgasagt: your immune against every virus
    also kurgesagt: explains how your not immune to every virus

  • Pro Veritate
    Pro Veritate 2 meses atrás +6826

    When I was 19, an erratic bat that crashed with almost every object around entered in my house, and when I tried to grab the creature to throw it back outside, it bit me. My mother was highly concerned about what just happened, she seemed almost hysteric and I of course thought she was overreacting. She took me to a clinic that same night and made me take the anti-rabies vaccine, the first shot of many that I had to take in order complete the treatment.
    Reading afterwards about the awful and agonizing death that rabies patients suffer when they are left unattended, I am very grateful to my mother for her urgency and don't wanna think too much about what would have happened if she hadn't been around to act so quickly and decidedly. Most probably I would have forgotten about the bite the next day and would have died in the next few months. She saved my life.

    • Nanuqo 2006
      Nanuqo 2006 Mês atrás

      a bot stole your comment bro

    • MikeDrop Sounds
      MikeDrop Sounds Mês atrás

      So wait, you didn’t turn into a vampire?

    • Twentysevenwithnecktats
      Twentysevenwithnecktats Mês atrás


    • Krzysztof Zukowski
      Krzysztof Zukowski Mês atrás

      @Die absolute Glücksküche for rabies that would be racoons. Saw a rabid one while working on the tracks. Bunch of obvious signs:
      -He was outside in the daytime
      -he was not afraid of us and the train that flew past him
      -He actually tried coming closer to us multiple times
      -he touched the third rail a few times, spazzed out everytime and kept walking as if nothing happened afterwards.
      -he was also a plump little guy so I dont think it was starting and desperate for food.

  • Gaehhn
    Gaehhn 29 dias atrás +1

    It's really curious how much the German and English versions of the same video sometimes differ. It makes me really glad that I know both languages and take the time to watch both.

    • Gaehhn
      Gaehhn 27 dias atrás

      @Subaru Can't deny that.

    • Subaru
      Subaru 27 dias atrás +1

      Show off

  • Get Up Now
    Get Up Now 15 dias atrás

    Surprisingly, rabies vaccines in many countries, especially the US, are so expensive. In Vietnam, it only costs about 5usd for 1 injection and almost everyone has injected at least 1 time

  • Hunter o Justice
    Hunter o Justice Mês atrás +1

    I have a question, what does the vaccine actually do? If the immune system can’t even find rabies how does the vaccine help?
    Genuine question.

    • Vanta Blacc
      Vanta Blacc Mês atrás +2

      Vaccines contain a weaker/enfeebled part of a pathogen (in this case - rabies) which allows your immune system to recognize and kill it easily. It prepares your Immune system and creates memory cells that can easily recognize and dispatch rabies if ever you get infected by it in the near future.

  • JackClayton123
    JackClayton123 Mês atrás

    I’m from Ontario, Canada. The government here also uses vaccinated bait to keep the wild animals from contracting rabies. As a result, it’s far less of an issue here.

  • Kj Gamer2614
    Kj Gamer2614 2 meses atrás +1840

    Rabies is truly terrifying. When you have it you may not know for months, but once you know your pretty much already dead. Lucky it’s not that common and hard to spread between people. I think only 1 person has ever survived so it’s maybe not deadly by amount of people, but by it’s effectiveness and death rate.
    Basically if you get bit by a mammal, immediately get a vaccine

    • B.A. Erlebacher
      B.A. Erlebacher 2 meses atrás

      @Jordan Bell coyotes and foxes are important carriers too.

    • alyssa
      alyssa 2 meses atrás

      @ahhhcool no onee cares

    • SFS Valiant /Jelly
      SFS Valiant /Jelly 2 meses atrás

      @ahhhcool stop Kurgestagt videos take 1200 hours to make due to animation and reasearch you should watch Jame's video AKA(Odd1sout) the video about the truth about animation

    • DaGamerGuy
      DaGamerGuy 2 meses atrás

      What the heck is going on in the replies

  • Grant M
    Grant M Mês atrás

    Just a thought, in your space tether video, on mars, you had the mega cable from Phobos reach out to Deimos. Since Phobos will eventually crash into mars and Deimos is going to drift away, do you think a tether In between would stabilize their orbits?

  • Tolulope_kizito
    Tolulope_kizito Mês atrás +1

    can we take a moment to appreciate whoever’s making these amazing animations 👏

  • JP Lavoie
    JP Lavoie Mês atrás

    As someone with an IQ of 2! I appreciate this. Thank you! 🙏

  • artemisqueen2
    artemisqueen2 Mês atrás

    As a public health professional in Canada we assess all animal bite cases to make sure there is no risk of rabies to the person bitten.

  • rashkavar
    rashkavar 2 meses atrás +2104

    I remember hearing that the first known person to survive an infection of rabies that reached the brain was kept in a particularly deep induced coma for the duration of their infection, which seemed to suppress the encephalitis and also gave the immune system a chance to fight back. And even then, they barely made it and had months of rehab to get over the coma.

    • Anastasia
      Anastasia Mês atrás +1

      There are a lot of absolute statements in this comment section, so let's break down a couple of things:
      The Milwaukee Protocol is complicated and controversial. *Since most rabies cases happen in developing countries* who don't have the funds for such a costly and time-consuming procedure, it hasn't been properly researched.
      The protocol has been attempted 38 times. 11 of these patients survived. Survival seems to be strongly associated with a very young age; *no one over 18 years old survived.* The surviving patients suffered from extreme neurological complications, and many are still severely disabled.
      The protocol clearly does have SOME value, as there were *zero* symptomatic survival cases prior to its creation. It's not nearly as simple as "it doesn't work so screw it", it is the *only treatment* that has ever shown any promise in preventing death in symptomatic patients. However, it clearly needs more research and funding.

    • True Vision
      True Vision 2 meses atrás

      Someone sent me this very serious interesting video (regarding Mental Health & The Creator). Alternatively, you can acquire it in Doc/PDF format, or read it online in the description box via directory link.

      Find it on * True Vision * and their BRclip channel, or insert the following title in to your BRclip Search Box: * G only is responsible for everything *.

    • Clipyy
      Clipyy 2 meses atrás

      @Bark Bark Kurzgesagt is correct on this one. Depends on the bite. Rarely months or years, but does happen. Usually 10days. Not a week.

    • Bagniacz
      Bagniacz 2 meses atrás

      @Ajay Dulani Rabies progression is ussually slow enough, in most cases doctors can just ask a patient if they want it.

  • Eiliria
    Eiliria Mês atrás

    Interesting stuff. I wish you discussed how the vaccine works and how the chicken heads infused with the vaccine vaccinated the animals if it wasn't given intravenously.

  • Anar Mehraliyev
    Anar Mehraliyev Mês atrás

    There was a girl who survived after displaying the symptoms thanks to the Milwaukee protocol.

  • Dangerous Noodle
    Dangerous Noodle Mês atrás +2

    I absolutely love how dynein motors are portrayed as scout walkers from star wars

  • Louis Yang
    Louis Yang Mês atrás +3

    Why this didn't cause a zombie outbreak it's actually simple. Since the rabid triggers the aggressive behavior, which includes biting in most animals. And we don't bite each other even when highly irritated. But it is possible if the virus behavior got some tweaks like triggering an insatiable hunger,and then we got the zombies.

    • CG
      CG Mês atrás

      Louis Yang
      Amazing someone should manufactured that